BackgroundBefore participation in medical research an informed consent must be obtained. This study investigates whether the readability of patient information and consent documents corresponds to the average educational level of participants in rheumatological studies in the Netherlands, Denmark, and Norway.Methods24 PICDs from studies were collected and readability was assessed independently using the Gunning’s Fog Index and Simple Measure of Gobbledygook grading.ResultsThe mean score for the FOG and SMOG grades were 14.2 and 14.2 respectively. The mean FOG and SMOG grades were (...) 12.7 and 13.3 in the Dutch studies, 15.0 and 14.9 in the Danish studies, and 14.6 and 14.3 in the Norwegian studies, respectively. Out of the 2865 participants, more than 57 % had a lower educational level than the highest readability score calculated in the individual study.ConclusionsAs the readability level of the PICDs did not match the participants’ educational level, consent may not have been valid, as the participants may have had a limited understanding of what they agreed to participate in. There should be more focus on the readability of PICDs. National guidelines for how to write clear and unambiguous PICDs in simple and easily understandable language could increase the focus on the readability of PICD. (shrink)

A hippocampal patient is described who shows preserved item recognition and simple recognition-based recollection but impaired recall and associative recognition. These data and other evidence suggest that contrary to Aggleton & Brown's target article, Papez circuit damage impairs only complex item-item-context recollection. A patient with perirhinal cortex damage and a delayed global memory deficit, apparently inconsistent with A&B's framework, is also described.

The value of accuracy and quantity as memory measures is assessed. It is argued that (1) accuracy does not measure correspondence (monitoring) because it ignores omissions and correct rejections, (2) quantity is confounded with monitoring in recall, and (3) in recognition, if targets and foils are unequal, both measures, even together, still ignore correct rejections.

After having defined the KARO logic for specifying intelligent agents in earlier work we now turn to the question how to realise agents specified in the KARO framework. To this end we look at agent programming languages that we have defined, and investigate how programs in these languages can be linked to the KARO logic.

This paper presents a framework for the generation of coherent elementary conversational sequences at the speech act level. We will embrace the notion of a cooperative dialogue game in which two players produce speech acts to transfer relevant information with respect to their commitments. Central to the approach is that participants try to achieve some sort of balanced cognitive state as a result of speech act generation and interpretation. Cognitive states of the participants change as a result of the interpretation (...) of speech acts and these changes provoke the production of a subsequent speech act. Describing the properties and the dynamics of the mental constructs that constitute the participants’ cognitive states, such as beliefs and commitments, in relation to the various dialogue contributions is an essential aspect of the game. Although simple in its basic form, the framework enables us to produce abstract conversations with some properties that agree strikingly with coherence structures found in, for instance, Conversation Analysis. (shrink)

A framework to explain item-specific implicit and explicit memory is proposed. It explores the mutual implications of four kinds of processing mechanism that are familiar in the literature. The first kind of mechanisms are those related to memory representation which include the kind of storage processes that subserve the maintenance of different types of information in memory. It is argued that there is very little evidence to suggest that fact and event memory require the postulation of algorithmically distinct kinds of (...) storage mechanism. The second mechanism is the enhanced fluency of activation of representation triggered by the encoding of components of those representations that results from the storage changes mediating memory. It is argued that enhanced fluency underlies all item-specific implicit memory and that the same kind of fluency process is probably involved regardless of the type of memory representation fluently activated. The third type of mechanism is the kind of attribution process that is triggered by fluency and gives rise to aware memory feelings as well as specific perceptual and aesthetic feelings The final mechanism is active search, which is an often present feature of explicit memory, and involves the effortful mediation of the frontal lobes. How the interactions between these different mechanisms accounts for item-specific implicit memory, recognition and recall is discussed, as is the framework's relationship with other current views about the mechanisms underlying memory. The best available methods of measuring enhanced fluency, familiarity, and recollection are reviewed so as to indicate the ways in which the framework may be tested. (shrink)